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Top 5 Hair Growth Serums of 2025: Clinically Tested Results According to a MD in Dermatology

Do hair growth serums really work? Find out what is tested and discover a doctors top picks.

If you’re starting to notice thinning or balding, hair growth serums seem like an obvious solution.

First, these serums are everywhere! And no wonder. Hair growth serums are far more affordable, less painful, and present fewer risks than hair transplants and medicated products.

But can a serum really regrow hair? Sure, any brand can find before and after pictures, but will it regrow your hair? That’s the question.

As a scientist and researcher, I can tell you what the clinical studies say and how to choose the best hair serums on the market right now.

Do Hair Growth Serums Really Work? Here’s What Science Reveals

My MD is in dermatology, which means I specialize in skin and hair health science. So, it’s not surprising that I became very intrigued by the potential of hair growth solutions.

I wanted to know if it’s possible for serums to affect growth without medicated ingredients. To find out, I did an extensive review of the clinical research.

As it turns out, hair serums (the best ones) contain active ingredients that do penetrate the scalp to the follicles and actively affect growth. Studies show that serums can influence hair growth in three ways:

  1. Reducing scalp inflammation to improve follicle health (thereby indirectly improving growth)
  2. Stimulating hair follicles to enter the growth phase or stay in the growth phase for a longer period
  3. Improving blood circulation to expand “shrunken” follicles and deliver nutrients needed for growth

This demonstrates that the science behind hair growth serums is sound.

How Do Hair Growth Serums Compare To Other Solutions

It’s clear that active ingredients in serums can help to grow hair back and fight hair loss in three important ways.

Are these the best ways to influence hair growth? I would argue yes.

The only other ways to regrow hair or prevent loss are to a) transplant hair follicles or b) block DHT (dihydrotestosterone), a hormone. Both of these come with more significant risks and unwanted side effects.

What Can You Realistically Expect From Hair Growth Serums?

Here’s the catch: All hair growth solutions (even transplants and medications) take time. Hair loss takes time, and so does growth. At best, you’ll notice a reduction in hair loss in about 6 weeks. New growth takes 3-6 or even 9 months sometimes.

Also, hair growth serums work best if your hair loss is relatively recent. (This is true for medications, too.) If you’ve had bald spots for years, nudging those follicles back into producing hair might be impossible.

How To Choose A Safe & Effective Hair Growth Serum

Now that you know what hair growth serums can do in theory, let’s look at which ones on the market, based on their ingredients, could potentially tick all three boxes.

We also want to look at safety. Hair growth serums are “use at your own risk” products. You may have heard of cult hair products that ultimately caused hair loss, bald spots, blisters, and even scalp injuries. I don’t want this to happen to you!

Here’s what we’ll look for:

Ingredients that…

  1. Promote a healthy scalp environment
  2. Extend the hair growth phase
  3. Improve circulation to the follicles
  4. Are recognized as safe for daily, long-term use

These are the four criteria I look for in a hair growth serum backed by evidence.

Top 5 Hair Growth Serums According to a Hair Science Researcher

Now you know what we’re looking for… Which hair growth serums make the cut?

Because I’m a researcher, I’ve only included products with ingredients backed by clinical research. Next, I factor in safety, customer results, and value for money

Notes:

  • All hair growth serums should be used daily, so convenience is not a factor in this ranking.
  • There are no extra points for brands that claim to grow hair more quickly. Hair grows slowly, no matter what. At best, you’ll see baby hairs in about six weeks but expect to wait months.
  • Texture and scent do not factor into this ranking. In this post, I’m focused on growth factors.

Here, you’ll find my top picks for 2025, ranked.

Bio-Pilixin was developed in Europe using relatively new stem cell technology.

The brand’s star ingredient, Bio-Pilixin, is backed by third-party clinical trials with men and women of all ages (and multiple types of hair loss.)

Here are the key clinical findings of the study reported after 150 days of usage:

  • 93.3% of volunteers showed a reduction in hair loss. The average hair loss reduction was 45.75%, with a maximum hair loss reduction of 85.08% (volunteer 26)
  • 73.3% of volunteers showed a significant improvement in hair density. Capillary density increased by up to 23.31% after the usage.
  • 17.5% increase in the number of hair in the anagen (growth) phase after 150 days. 36.5% decrease in the number of hair in the telogen (rest) phase after usage.
  • 80% of volunteers reported a moderate-to-intense hair loss reduction.
  • 93.3% of volunteers reported being satisfied with the hair loss usage.

Scandinavian Biolabs’ Bio-Pilixin® Activation Serum is backed by a 150-day money-back guarantee. Their serum and other hair growth products are available for men and women.

CHECK AVAILABILITY FOR MEN
CHECK AVAILABILITY FOR WOMEN

Also, the cost can be prohibitive. Ounce for ounce, Vegamour is almost 3x the price of the top-rated growth serum.

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